Assessment of recently developed blood gasanalysers: a multicentre evaluation

[摘要] Providing guidelines for testing expected inaccuracy and imprecisionis still a matter under debate. The Expert Panel of the FrenchSociety of Clinical Chemistry has developed a protocol, which wasbased on a comparative multi-centre evaluation of four instruments:the Ciba-Corning 278, the Instrumentation Laboratory 1306, theNova SP 5 and the ABL 330. The purpose was to evaluate theanalytical performance and efficiency of the analysers. Another aimwas to design a valid approach for evaluating any new system. Asbuffered aqueous solutions and fluorocarbon emulsions give onlypartial information, tonometered blood was used at different levelsof gas mixture, even though it is both difficult and time-consuming.Comparisons have been established on patients' blood samples withthe analysers currently used in the evaluation sites. The tests showedthat the four analysers have the same degree of precision, and interinstrumentcomparisons demonstrated a very high degree ofreliability.This analysis emphasizes that the evaluation of instruments forpH and blood gas analysis is neither easy nor is it often done,mainly due to the choice of a quality-control material and thelability of the measured parameters.

[学科分类] 分析化学