The Effect of Cromolyn Sodium and Nedocromil Sodium Administered by A pressurized Aerosol with A spacerDevice on Exercise-Induced Asthma in Children

[摘要] To compare the effectiveness of cromolyn sodium (CS)(10 mg) and nedocromil sodium (NS) (4 mg) administeredby a metered dose inhaler (MDI) with a spacerdevice in preventing exercise-induced asthma (EIA), eightasthmatic children with EIA were studied in arandomized double-blind, cross-over, placebo-controlledstudy, CS and NS provided significant, comparable protectionfrom EIA and both were better than placebo. Weconclude that CS and NS administered by a pressurizedaerosol with a spacer device provide equal protectionagainst EIA in children.

[学科分类] 生理学与病理学