Modified Newton-Raphson Method to Tune Feedback Gains of Control System for Standing by Functional Neuromuscular Stimulation Following Spinal Cord Injury

[摘要] Background: Functional neuromuscular stimulation (FNS) can restore standing capabilities following spinal cord injury.Feedback control of these systems can optimize performance by reducing the required upper extremity support. However, tuningthese control systems can be intensive and clinically inconvenient.Objective: This case study investigated a clinical method to efficiently tune feedback gains for a control system utilizingfeedback of total body center of mass acceleration to modulate stimulation levels to targeted paralyzed musculature of the lowerextremities and trunk.Methods: Gains for this control system were tuned to minimize the stabilization loading by one arm against internal posturalperturbations volitionally-generated during manipulation of an object using the other arm. An algorithm based on a modifiedform of the Newton-Raphson method was employed to find the optimal feedback gains with lower subject effort than that todetermine the original tuning curves.Results: This method accurately (<6.2% error) approximated the optimal gains with 70% fewer manipulations by the subject.Conclusions: These results suggest that optimal feedback gains for the specific FNS control system can be determinedsystematically with considerably less effort than heuristic gain tuning. This demonstrates the potential for devising simple,convenient methods for effective system re-tuning during clinical usage.

[学科分类] 生物技术