Maternal Group B Streptococcal (GBS) Genital TractColonization at Term in Women who Have AsymptomaticGBS Bacteriuria

[摘要] Objective:To determine the rate of positive group B streptococcus (GBS) cultures at 35–37 weeks gestationin women who have first trimester asymptomatic GBS bacteriuria.Methods:Pregnant women with asymptomatic first trimester GBS bacteriuria had genital cultures for GBSperformed at 35–37 weeks gestational age. Serotyping was performed by the standard Lancefield capillaryprecipitin method.Results:Fifty-three women with positive urine cultures had genital cultures performed at 35–37 weeks. Sixteenof the 53 (30.2%; 95% confidence interval: 18.4–44.3%) third trimester vaginal cultures were positive for GBS.Five of eight (63%) of the women with typable urine serotypes had the same typable serotype in the thirdtrimester genital culture.Conclusion:Genital tract cultures at 35–37 weeks for GBS correlate poorly with first trimester asymptomatic GBSbacteriuria. Recommendations for GBS prophylaxis in labor in women who have first trimester asymptomaticGBS bacteriuria should be investigated further and reconsidered.

[学科分类] 妇产科学