Etiology of Persistent Tubo-Ovarian Abscess in Nairobi, Kenya

[摘要] ObjectiveTo study the microbial etiology of tubo-ovarian abscess (TOA).MethodsWe recruited 11 women in Nairobi, Kenya who failed antibiotic therapy alone and requiredsurgical drainage of a presumptive TOA. Pus from the nine abscesses and two pyosalpinges were collected andcultured for aerobic, facultative and anaerobic microorganisms.ResultsEleven women suspected of having a TOA were hospitalized and treated for a median of 6 days (range3–14 days) prior to surgical drainage of the abscess. Nine (82%) specimens were culture positive. Aerobeswere present in all nine specimens. Seven of the nine positive cultures (78%) were polymicrobial and five ofthe polymicrobial cultures contained both anaerobes and aerobes. Anaerobic Gram-negative bacilli (Prevotella sp.,Porphyromonas sp. and Bacteroides sp., Escherichia coli) and Streptococcus sp. (S. viridansandS. agalactiae) were themost common microorganisms isolated.Neisseria gonorrhoeaeandChlamydia trachomatiswere not isolated byculture or detected by polymerase chain reaction.ConclusionsIn Kenya, persistent TOAs are associated with endogenous flora similar to that normally foundin the gastrointestinal tract.

[学科分类] 妇产科学