Interrelationships Within the Bacterial Flora of the Female Genital Tract

[摘要] Analysis of 240 consecutive vaginal swabs using the compatibility profile technique revealed that only 2 bacteria have the ability to be a sole isolate and as such a candidate to be a major aerobic regulator of the bacterial flora of the female genital tract (BFFGT). Compatibility profiles ofLactobacillusandGardnerella vaginalishave shown that these organisms shared compatibility profiling for the majority of the normal bacterial constituents of the female genital tract. Dominance disruption appears to come from the addition of compatible co-isolates and presumed loss of numerical superiority. These phenomena appear to be the keys to reregulation of BFFGT.Lactobacillusappears to be the major regulator of bothG. vaginalisand anaerobic bacteria. When additional organisms are added to the bacterial flora, they may add to or partially negate the inhibitory influence ofLactobacilluson the BFFGT. Inhibitor interrelationships appear to exist between coagulase-negative staphylococci andStaphylococcus aureusand the group B streptococci (GBS) and other beta hemolytic streptococci. Facilitating interrelationships appear to exist betweenS. aureusand the GBS and selectedEnterobacteriaceae.

[学科分类] 妇产科学