In Vitro Susceptibility ofUreaplasma urealyticumandMycoplasma hominisIsolates in Argentina

[摘要] Objective:Our goal was to determine the in vitro susceptibility ofUreaplasma urealyticumandMycoplasma hominisisolates to several antibiotics in Argentina.Methods:Ninety-four strains ofU. urealyticumand 18 strains ofM. hominisisolated from cervical and urethral specimens were studied. Broth microdilution and agar dilution tests for minocycline, tetracycline, erythromycin, ciprofloxacin, and ofloxacin were performed.Results:Both methods proved to be reliable and reproducible forU. urealyticumandM. hominis, with no major differences in results. TheU. urealyticurnstrains were inhibited by erythromycin at MICs ranging from ≤0.5 to >8 μ/ml. Ofloxacin showed the highest activity against this latter organism. No differences between tetracycline and minocycline MICs were observed withU. urealyticum. TwoM. hominisstrains displaying high MICs both to tetracycline and to minocycline were detected.Conclusions:The emerging resistance of mycoplasmas to certain antibiotics emphasizes the need to undertake further surveillance studies on the clinical isolates of such organisms.

[学科分类] 妇产科学