Vaginal Colonization bypapGAllele II+Escherichia coliIsolates from Pregnant and Nonpregnant Women as Predisposing Factor to Pyelonephritis

[摘要] Vaginal (61) and fecal (61)Escherichia coliisolates from pregnant and nonpregnant women (18–45 years old) were surveyed forpapGalleles by PCR technique.papGallele II was the most prevalentamong both vaginal (32.7%) and fecal (3.2%) isolates, whereas other alleles were found only among vaginal isolates(1.6% for alleles I and III and 3.2% for alleles II + III).papG+pregnant women's isolates didnot differ significantly from those of nonpregnant in possession ofpapGallele II (90% versus 73.3%),whereas both (32.7%) differed significantly(P≤0.05) in comparison with fecal isolates (3.2%). The vast majority ofpapGallele II+vaginal isolates were clustered in group B2 (81.8%) and much less in group D (18.1%). Also, most of them were positive forfimH(100%),papC(100%),iucC(90.9%), andhly(72.7%), and about half of them were positive forsfa/foc(45.4%). In addition, the mean of VFs' gene possession was 3.5 (range from 2 to 5). It can be concluded that vaginal colonization bypapGallele II+E. coliis possibly one of the predisposing factors of both pregnant and nonpregnant women to pyelonephritis, but its potential may be modified by other factors especially host factors.

[学科分类] 妇产科学