Chorioamnionitis: Association of Nonreassuring Fetal Heart-rate Patterns and Interval From Diagnosis toDelivery on Neonatal Outcome

[摘要] Objective:The purpose of this study was to determine whether selected fetal heart-rate (FHR)patterns and the interval from diagnosis to delivery in pregnancies complicated by chorioamnionitiscould predict neonatal outcome.Methods:During a 6-month period, 217 consecutive patients with acute chorioamnionitis wereprospectively identified in labor. Following delivery, the fetal monitor strips and hospital courseswere reviewed for both the mother and neonate. Multiple logistic regression was used to analyze thepresence of a nonreassuring FHR pattern and the effect on neonatal outcome. Fisher exact testswere used to analyze the time intervals from the diagnosis of chorioamnionitis to delivery and theirsignificance on neonatal outcome parameters.Results:The overall incidence of chorioamnionitis in our population was 2.3%. None of theindependent variables analyzed following the diagnosis of chorioamnionitis until delivery weresignificantly associated with an umbilical artery (Ua) pH < 7.20. There were no differences in cordpH, Apgar scores, sepsis, admission to special-care nursery, and oxygen requirements in neonatesbased on the duration of time from the diagnosis of chorioamnionitis to delivery in our study. None ofthe newborns had pathologic fetal acidemia (Ua pH < 7.00). None of the FHR patterns weidentified after the diagnosis of acute chorioamnionitis were significantly associated with neonateswith a Ua pH < 7.20.Conclusions:An interval from diagnosis to delivery of up to 12 h plays little if any role in neonataloutcome.

[学科分类] 妇产科学