Prevalence of Human Papillomavirus,Chlamydiatrachomatis,andNeisseria gonorrhoeaein CommercialSex Workers in Japan

[摘要] Objective:We used the hybrid capture assays to investigate the prevalence of human papillomavirus(HPV),Chlamydia trachomatisandNeisseria gonorrhoeaeamong commercial sex workers in Tokyo.Methods:Five hundred forty-six consecutive commercial sex workers (CSW) who visited anSTD clinic for STD checkup in 1998 and 1999 were studied. A control group consisted of 233consecutive women who visited a general gynecological clinic for annual checkup. A cervicalsample was obtained for hybrid capture assays for HPV-A (low-oncogenic-risk types), HPV-B(intermediate- and high-oncogenic-risk types),C. trachomatis, andN. gonorrhoeae. Fisher's exacttest was used for statistical analyses.Results:The positive rate for HPV-B among the CSW was 48.4%, significantly higher than the6.0% among the control subjects. The positive rates for HPV-A,C. trachomatis, andN. gonorrhoeaewere also significantly higher among the CSW than among the control subjects. Among the microorganismstested, the positive rate for HPV-B was the highest in both the STD and controlgroups.Conclusions:The high prevalence of HPV,C. trachomatis, andN. gonorrhoeaeinfection in CSWposes a risk of further transmission of STD to the general public, suggesting the need for furthereducation and screening for CSW and the general public. We found high- and intermediateoncogenic-type HPV to be the most prevalent infection among both CSW and control subjects.Screening for HPV may be necessary in STD and general clinics to predict the risk of cervicalmalignancy. Hybrid capture assays, which permit simultaneous detection of HPV and other STDwith high sensitivity, may be a useful diagnostic method. Infect. Dis. Obstet. Gynecol. 8:235–239,2000.

[学科分类] 妇产科学