Detection ofCandidaSpecies in Vaginal Samples in a Clinical Laboratory Setting

[摘要] Objective.To present the detection rates ofCandidaspecies in vaginal samples from patients visiting physicians.Methods.The presence ofC. albicans, C. glabrata, C. parapsilosisandC. tropicalisin 3978 vaginal swabs from patients in six US states was detected by PCR amplification.Results.Candida DNA was detected in 33.1% of the population studied. Of the 1316 positive samples, 80.2% containedC. albicans, 14.3% containedC. glabrata, 5.9% containedC. parapsilosisand 8.0% containedC. tropicalis. Comparing samples by patients' state of residence revealed an association with the detection ofC. glabrata(p=0.029). Comparing samples bypatients' age revealed a decrease in the overall detection ofCandida(p< 0.001) andC. albicans(p< 0.001), concomitant with an increase in the detection ofC. glabrata(p< 0.001) andC. parapsilosis(p= 0.025).Conclusions.These results provide geographic- and age-specific data on fourCandidaspecies associated with vaginitis.

[学科分类] 妇产科学