Chlamydia trachomatisSerology in Women with and without Ovarian Cancer

[摘要] Pelvic inflammation has been implicated in the genesis of ovarian cancer. We conducted serologic measurements ofChlamydia trachomatisantibodies as a surrogate marker of chlamydial pelvic inflammatory disease.Women with ovarian cancer (n=521) and population-based controls (n=766) were tested.IgG antibodies to serovar D of chlamydia elementary bodies (EBs) were detected using an ELISA assay.The odds of having ovarian cancer among women with the highest titers (≥0.40 OD units) were 0.6 (95% CI 0.4–0.9).These data do not support our earlier finding of elevated titers for antibodies toC. trachomatisamong women with ovarian cancer.

[学科分类] 妇产科学