Response surface modeling and optimizing conditions for anthocyanins extraction from Hibiscussabdariffa L. (Roselle) grown in Lam Dong, Vietnam

[摘要] Hibiscus sabdariffa L. (Hs, roselle; Malvaceae) is a common ingredient used in the food and pharmaceutical industries for color and health benefits. Anthocyanins along with protocatechuic acid and quercetin have been recognized as bioactive compounds in Hibiscussabdariffa L. aqueous extracts. In this work, Response Surface Methodology was implemented together with Box-Behnken experimental design to investigate the impacts of process variables on anthocyanin extraction yields from Hibiscus sabdariffa L. (Roselle) grown in Lam Dong, Vietnam. The effects of three independent variables; namely the extraction temperatures of solvent ethanol (X1); the duration of extraction (X2); solid-liquid ratios (X3) on the total anthocyanins content (Y1) were explored. The optimization model showed that with the solid liquid ratio 7.7:1, extraction time 33.29 min, and temperature 56.9C, the highest anthocyanin concentration of 186.006 mg/L was obtained. Hibiscussabdariffa L. anthocyanin yield detailed significant correlation with high F values, low P values (

[发布机构] NTT Hi-Tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City, Viet Nam^1;Faculty of Chemical Engineering and Food Technology, Nguyen Tat Thanh University, Ho Chi Minh City, Viet Nam^2;Graduate School of Biotechnology, Kyung Hee University, Korea, Republic of^3;Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, Ha Noi, Viet Nam^4;Department of Chemical Engineering, HCMC University of Technology, VNU-HCM, Ho Chi Minh City, Viet Nam^5;Faculty of Chemical and Natural Resources Engineering, Universiti Malaysia Pahang, Malaysia^6

[效力级别] 材料工程

[关键词] Box-Behnken experimental design;Determination coefficients;Experimental verification;Extraction temperatures;Optimization modeling;Pharmaceutical industry;Response surface methodology;Response surface modeling