Source of collagen at epitheliomesenchymal interfaces during inductive interaction☆
[摘要] Thedatareportedindicatethatembryonicsalivarymesenchyme,initiallylabeledwithtritiatedprolineorglycine,transmitsalabelablematerialacrossafiltermembranebetweenthemesenchymeandsalivaryepithelium.Thematerialaccumulatesattheepithelialsurfacewithadistributionsimilartothatofultrastructurallyidentifiablecollagen.Thesuggestionthatthelabelactuallyisincollagenisinconformitywith,butnotconclusivelydemonstratedby,thefactsthatcollagenisrichinprolineandglycineandthelabelisremovedbycollagenasetreatmentofsectionsbutnotbyhyaluronidasetreatment.Ontheotherhand,embryonicsalivaryepitheliuminitiallylabeledwithprolineorglycinedoesnotsimilarlydepositlabelinapatternwhichcoincideswiththedistributionofcollagen.Thedataareinterpretedtofavorthehypothesisthatbasementmembraneformationinvolvestransferofsolubletropocollagenfromthemesenchyme,whereitissynthesized,totheepithelialsurface,whereitispolymerized.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
