Loss of ascorbic acid synthesis in embryonic development☆
[摘要] Theexperimentsreportedhereshowthatgulonolactoneoxidase—theenzymecatalyzingthesynthesisofascorbicacidfromgulonolactone—iswidelydistributedintheearlychickblastodermandthatinthecourseofdifferentiationthissyntheticactivitydisappearsfromalltissuesexaminedexceptthekidney,whereitconcentrates.Thisparallelstheevolutionarylossofascorbicacidsynthesis,whichhasbeenshowntobeduetothedeletionofthisenzyme.Inthechickembryo,asinadultanimals,gulonolactoneoxidaseismostabundantinthemicrosomes.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]