Cell cycle changes during growth and differentiation of imaginal leg discs in Drosophila melanogaster☆
[摘要] TherelativeDNAcontentofDrosophilamelanogasterimaginallegdiscnucleiduringlarvalgrowthandpupalandadultdifferentiationwasmeasuredbymicrospectrophotometry.Duringthelarvalproliferativephasethereweretwiceasmanynucleiinthe4Cclassasnucleiinthe2Cclass.Attheendofthethirdlarvalinstar,theproportionofnucleiwitha4CDNAvalueincreased.By3hrafterpupariation,duringpupalcuticlesecretion,90%ofthenucleiwereinthisclass.Afterpupalapolysiswhichoccursat12hrafterpupariation,the4Cto2Cratiowasreversed.Theincreaseintheproportionofnucleiwitha2Cvaluewasobserveduntil24hrafterpupariationwhen90%ofthenucleiwereinthisclass.Weproposethatmostcellsdivideatleastoncebetweenpupalandadultdifferentiation.Allofthesechangesinthecellcyclewerecorrelatedtemporallywithchangesintheecdysteroidtitersthatoccurduringtheseperiods.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]