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Developmentally regulated transcription from Drosophila melanogaster chromosomal site 67B☆
[摘要] WehaveclonedandcharacterizedaninsertoftheDrosophilamelanogastergenomechosenforstudybecauseitishomologoustoRNAexpressedmoreabundantlyinearlypupaethaninembryos.Thisinsertcontainsaclusteroffivetranscriptcodingsegmentswithin8.5kilobases.Allofthetranscriptsthatwedescribearedevelopmentallyregulated,beingatmaximalabundanceinlate-third-instarlarvaeandearlypupae,andnotdetectableorveryrareinthird-instarlarvaeabout1daypriortopupariumformationandinlatepupae.Someofthetranscriptsaredetectableatlowlevelsinembryos.Unexpectedly,thisclonedinsertoverlapsthepreviouslydescribedheat-shockgeneclusteratcytologicallocation67B.Sequentially,wefindapreviouslyunknowncodingsegmentwithintheheat-shockcluster,thetwoheat-shockcodingsegments,andtwomorepreviouslyunknowncodingsegmentsbeyondtheheat-shockcodingsegments.Thus,twogeneswhichareinducedbyheatshockarealsofoundtobeexpressedwiththedevelopmentalregulationdescribedabove.
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[效力级别]  [学科分类] 生物科学(综合)
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