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Pattern formation during early amphibian development: Embryogenesis in inverted anuran and urodele eggs☆
[摘要] EarlyembryogenesiswasmonitoredinXenopus,Rana(anurans),andAmbystoma(urodele)eggswhichwereinvertedatvarioustimesbetweenfertilizationandfirstcleavage.Thepatternofcleavagefurrowformation,siteofinvolution,andextentoforganogenesiswereobserved.Inseveralinstances,patternformationwasdramaticallyaltered.Thesmall/largeblastomerepatternwas,forexample,reversedinsomeinvertedembryos.Developmentalarrestatearlyorganogenesisusuallyfollowedpatternreversal.Byemployingaseriesoftissuetransplantations,itwaspossibletoestablishthattheactivityoftheprimaryembryonicorganizerofinvertedembryoswasdiminisheddrastically.Thedevelopmentalcompetenceoftheprospectiveectodermofinvertedembryoswas,however,reversed.Incompleteorganogenesisininvertedembryosisthereforeprobablyduetoeitherabnormalmesodermformationordefectivetissueinteractions.
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[效力级别]  [学科分类] 生物科学(综合)
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