Translationally mediated changes in patterns of protein synthesis during maturation of starfish oocytes☆
[摘要] WhenmeioticmaturationofprimaryoocytesofthestarfishAsteriasforbesiisinducedby1-methyladenine,rapidandstrikingchangesinthepatternofproteinsynthesisdetectablebyelectrophoresisoccuraftergerminalvesiclebreakdown.Theseincludeadeclineinrelativelabelingwith[35S]methionineofseveralpolypeptidessynthesizedintheoocyte,andincreasedlabelingandnewappearanceofseveralpolypeptides.Fertilizationdoesnotresultinotherdetectablechanges.ThepopulationoftotalmRNAtranslatableinarabbitreticulocytelysatecell-freesystemdoesnotchange,butthedistributionofmRNAsbetweenpolysomesandthepostribosomalsupernatantreflectsthechangesobservedinvivo.Thusthesechangesareregulatedatthetranslationallevel.Areviewoftheliteratureindicatesthattranslationallymediatedchangesinpatternsofproteinsynthesisduringmaturationofoocytesmaybeawidespreadphenomenon.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
