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Axon growth from limb motoneurons in the locust embryo: The effect of target limb removal on the path taken out of the central nervous system
[摘要] Removalofthemetathoraciclimbbudfromlocustembryosat25to30%ofembryogenesishasaspecificeffectontheoutgrowthofaxonsfromaparticulargroupofmotoneurons:nerveroot5ismissingintheseanimalsandtheneuronswhichnormallysendaxonsoutthisnerveleavetheganglionbynerveroots3and/or4.Thechoiceofexitpathwaymadebyindividualidentifiedaxonsisvariable.Whenremnantsofthemetathoraciclegwhichincludetracesofthefemurarepresentaftertheoperation,nerve5ispresentandcontainsanormalcomplementofmotoraxons.Thissuggeststhatinnormaldevelopmentsomefactorneartheanlageofthecoxal-femoraljointspecifiesthepathwaytakenbytheaxonsofnerve5motoneuronsoutofthemetathoracicganglion.Twoperipheralneuronsseeninthisregionofthelimbbudinprekatatrepsisembryosarelikelycandidatesforthisrole.
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[效力级别]  [学科分类] 生物科学(综合)
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