Nuclear morphology of ichthyosis mutant mice as a cell marker in chimeric brain☆
[摘要] Thenuclearmorphologyofcertainneuronalpopulationsfromthemutantmouse,ichthyosis,isdistinctfromwild-typestrainsofmice.Thegranulecellsofthecerebellum,cochlearnucleus,andolfactorybulbinichthyosismicehaveamuchgreatertendencyforcentralizedclumpingofnuclearheterochromatin.Intheearlypostnatalnervoussystemmanycellsinmigratoryandgerminalregionsofthebrainalsoexpresstheichthyosisphenotype.Theretentionoftheichthyosisphenotypeinneuronsofchimericmiceisdocumented.Theprevalentexpressionoftheichthyosisphenotypeinpostnatalmigratoryandgerminalregionsofthebrainwouldbeparticularlyusefulforstudyingcellinteractionsinthedevelopingbrain.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
