Chick endogenous lectin enhances chondrogenesis of cultured chick limb bud cells
[摘要] Wehavestudiedtheeffectofβ-d-galactoside-specificlectinpurifiedfrom14-day-oldchickembryosonthedifferentiationofthemesenchymalcellsdissociatedfromthelimbbudsofstage24chickembryos,usingthemicro-massculturemethoddescribedpreviously.Whenthecellswereincubatedwiththelectinduringtheinitial12hrofculture,cellproliferationbecameslightlyactivated.Thelectin-treatedcellsformedagreaternumberofcartilagenodulesandincorporatedabouttwiceasmuchas[35S]sulfatepercellthanthecontrolcultures.Theresultsofthisstudyshowthatthechickendogenouslectinpromotescartilagedifferentiationinvitroandthatendogenouslectinmaypossiblybeinvolvedinchondrogenesisinvivo.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
