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Ammonia and other weak bases applied at any time of the hormone-dependent period inhibit 1-methyladenine-induced meiosis reinitiation of starfish oocytes☆
[摘要] Theeffectofweakbasesonstarfishoocytematurationinducedby1-methyladenine(1-MeAde)wasinvestigated.Ammoniumchloride,nicotine,andprocaineinhibitedmeiosisreinitiationinducedbyeither1-MeAdeordithiothreitol.TheinhibitoryeffectoftheweakbaseswashighlydependentonthepHofseawaterandincreasedwiththeincreaseinpH.Theseweakbasesneitherinhibitednordelayedmeiosisreinitiationwhengivenaftertheendofthehormone-dependentperiod,theperiodduringwhich1-MeAdeisrequiredformeiosistooccur,whereastheyblockedhormoneactionwhenaddedjustbeforetheendofthehormone-dependentperiod.
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[效力级别]  [学科分类] 生物科学(综合)
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