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Development of teratomas from yolk sac of genetically sterile embryos☆
[摘要] Yolksac-derivedteratomasarecomposedofvariouswell-differentiatedtissues.Thesetissuesmustbederivedfrommultipotentcells.ToexcludeagermcelloriginfortheseteratomasweusedSteel-Sl+femalescopulatedwithSl+males.Theembryosgeneratedfromsuchmatingcomprise25%SlSlsterileembryos,deficientinprimordialgermcells,25%normalembryos(+/+),and50%heterozygotes(Sl+).Theresultsindicatethatthegenotypeoftheembryosdoesnotinfluencethedevelopmentofteratomas.Displacedyolkssacsbelongingtogeneticallysterileembryosdevelopedintoteratomasasfrequentlyasthosefromheterozygotesandfromgeneticallynormalembryos.
[发布日期]  [发布机构] 
[效力级别]  [学科分类] 生物科学(综合)
[关键词]  [时效性] 
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