Characterization of a rat yolk sac carcinoma cell line☆
[摘要] Acontinuouscelllinewasestablishedfromanexperimentallyinducedratyolksaccarcinoma.Intheearlypassagesbothvisceralandparietalyolksaccarcinomawerepresent(designatedL1).Whenthecelllinewasreestablishedincultureafterserialtransplantationsinrats,onlyparietalyolksaccarcinomacouldbeidentified(designatedL2).Thiscelllineexpressesparietalyolksacendodermcharacteristicsinthatitsynthesizesbasementmembranecomponents,inparticular,laminin,butalsoentactin,collagenIV,andheparansulfateproteoglycan.Inaddition,anoncartilagechondrotinsulfateproteoglycanissynthesized.ThisratyolksaccarcinomacelllineL2willbeavaluablemodelforthestudyofbasementmembranecomponents.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]