Clonal analysis of vertebrate myogenesis: V. Nerve-muscle interaction in chick limb bud chorio-allantoic membrane grafts
[摘要] Theclonablecellpopulationsofinnervatedandnoninnervatedchorio-allantoicmembrane(CAM)graftsofearlychickembryolegbudshavebeencompared.Co-graftsofstage21or22legbudswithstage22–26spinalcordsegmentsexhibitaneartwofoldgreaterproportionofclonablemusclecellsthannoninnervatedcontrolgrafts(legbudalone).Astatisticallysignificantincreaseisapparentbythe8thgraftday.Graftsconstructedofstage17–20legbudsplusspinalcordandgrownforupto11daysdonotexhibitaproportionofmyoblastsgreaterthannoninnervatedcontrols.Thisstimulationofrelativemusclecellcontentsuggestsaroleofmotornervesinregulationofthesingle-cellpopulationofdevelopingskeletalmuscle.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
