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The development of the retino-tectal projection in Rana pipiens☆
[摘要] Thedevelopmentoftheretino-tectalprojectioninRanapipienshasbeenstudiedbytheintraocularinjectionofsmallamountsof[3H]prolineatlateembryonicandatseverallarvalstages.Aftersurvivalperiodsvaryingfrom1–24hrthedistributionoftheradioactivelylabeledproteinsintheaxonsoftheretinalganglioncellswasstudiedautoradiographically.Itisevidentfromtheappearanceoflabeledproteinsintheopticnerveandchiasmatlateembryonicandearlylarvalstagesthatthereisarapidphaseofaxonaltransportatthesestagesandthatsomefractionofthematerialstransportedinthisphasearedistributedtothetipsofthegrowingaxons.ThefirstretinalfibersreachthecontralateraloptictectumatembryonicStage22;atthisstagetheyareconfinedtotherostrolateralportionofthetectumwherethefirsttectalneuronsaregenerated.Atsuccessivelylaterstagesthefibersappeartogrowacrossthesurfaceofthetectuminageneralrostrolateraltocaudomedialdirection,reachingthedorsalpartofthemid-tectumatlarvalStageIIandthelateralpartofitscaudalthirdbyStageV.However,itisnotuntilrelativelylatelarvalstages(XVIII)thatthefibersreachthecaudomedialregionofthetectum,anditisonlyatthetimeofmetamorphosis(StageXXV)thattheretinalprojectionappearstocovertheentiretectum.
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[效力级别]  [学科分类] 生物科学(综合)
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