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Inhibitor of ribosomal RNA synthesis in Xenopus laevis embryos: V. Inability of inhibitor to repress 5S RNA synthesis☆
[摘要] AspecificinhibitorofribosomalRNA(rRNA)synthesiswaspartiallypurifiedfromanacid-solublefractionofXenopuslaevisblastulae.Effectsofthisinhibitoron5SrRNAsynthesisofisolatedneurulacellsofthesamespecieswereinvestigated.Theresultsshowthatthesynthesisofboth5SrRNAand4SRNAproceedsnormallywhenboth18and28SrRNAarealmostcompletelyinhibited.Failureoftheinhibitortosuppress5SrRNAsynthesissuggeststhatitplaysanimportantroleintheregulationof18and28SrRNAsynthesisduringdevelopmentandthatthesynthesisof5SrRNAisnotcoordinatedtothatof18and28SrRNA.
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[效力级别]  [学科分类] 生物科学(综合)
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