Aminoacyl-tRNA binding activity in regenerating kidney following contralateral nephrectomy or administration of folic acid☆
[摘要] Homogenatesofkidneycortexobtained2or7daysfollowingcontralateralnephrectomyorfolicacidinjectionwereseparatedintoaribosomefractionandintoapostmicrosomalpH5supernatantfraction.Theactivityofeachofthesefractionsforpeptidesynthesisfrom[14C]phenylalanyl-tRNAwastestedbycomplementationwithsimilarfractionsobtainedfromnormalratliver.Whiletheribosomalactivityofregeneratingkidneywasnotchanged,therewasanincreaseintheactivityofthepH5supernatantfractionobtainedfromregeneratingkidney.TheresultsprovidedevidencethattheincreasedincorporationobservedwiththepH5supernatantfractionobtainedfromregeneratingkidneywasduetoanincreasedactivityofelongationfactor1.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]