Modulations of histone messenger RNA during the early development of Xenopus laevis☆
[摘要] TheamountoftranslatablehistonemRNAinXenopusoocytes,eggs,andembryoswasfoundtoberoughlysimilar,asjudgedbyacell-freetranslationassay.Thisobservationprovidesfurtherevidencethatposttranscriptionalcontrolmechanismsbringaboutthe50-foldincreaseintherateofhistonesynthesisduringoocytematuration.Aboutthree-quartersoftheoocytehistonemRNAwasfoundtobepolyadenylated.However,polyadenylatedhistonemRNAwasscarcelydetectableintheeggandembryo.Ourdataareconsistentwiththespeculationpresentedherethatthedisappearanceofthepoly(A)+histonemRNAcomponentatthetimeofconversionofoocytetoegg(maturation)isduetodeadenylation.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
