Projection of sensory neurons from a homeotic mutant appendage, Antennapedia, in Drosophila melanogaster
[摘要] Centralprojectionsofsensoryneuronsfromhomeoticmutantappendages(Antennapedia)ofDrosophilamelanogasterwerecomparedwiththoseofwild-typeantennaeandwild-typelegsbymeansofdegenerationandcobaltbackfillingmethods.Sensoryaxonsoriginatingfromwild-typethoraciclegsterminatewithintheventralipsilateralhalfofthecorrespondingneuropilesegmentanddonotprojecttothebrain.Sensoryfibersfromthethirdantennalsegment(AIII)ofwild-typeanimalsprojectintotheipsilateralantennalglomerulus(AG)andtoalesserextentintothecontralateralAG,whereasthosefromthesecondantennalsegmentterminateprincipallywithintheipsilateralposteriorantennalcenter.Thesensoryterminalsoffemur,tibia,andtarsiofthehomeoticlegshowadistributionverysimilartothatofthehomologouswild-typeantennalsegmentAIII,differingtoaminordegreeonlyinthesizeandpreciselocalizationofterminalswithintheantennalglomeruli.Nodegeneratingaxonswereevidentinultrastructuralexaminationofneckconnectivesafterremovalofhomeoticlegs.Itisthusveryimprobablethatanysensoryfibersofthehomeoticlegprojecttonormallegprojectionareasinthethoracico-abdominalganglion.Severalalternativeexplanationsareofferedfortheapparentretentionofantennalspecificitybyaxonsfromthetransformedappendage.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
