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Retinal-tectal connections in the embryonic chick: Evidence for regionally specific cell surface components which mimic the pattern of innervation☆
[摘要] Supernatantsolutionsobtainedfromchickembryoopticlobeculturescontainmacromolecularcomponentswhichspecificallyinteractwithcellsobtainedfromneuralretinainawaywhichreflectstheinvivopatternofinnervationofthetectumbyretinalaxons.[14C]Glucosamine-labeledsupernatantswerepreparedfromeitherdorsalandventraloranteriorandposterioroptic-lobehalvesandtestedfortheirabilitytobindtoandinhibitcapformationofConcanavalinAreceptorsoncellspreparedfromdorsal,ventral,nasal,ortemporalretinaquadrants.Inallcases,preferentialbindingandinhibitionofcapformationcanbecorrelatedwiththepatternofinnervationoftheopticlobesbyretinalfibers.
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[效力级别]  [学科分类] 生物科学(综合)
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