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Secondary lens formation caused by implantation of pituitary into the eyes of the newt, Notophthalmus☆
[摘要] Wholepituitaryglands,aswellasequivalent-sizedpiecesofkidney,liver,andadrenaltissue,wereimplantedintotheanteriorchamberoftheadultnewteye.Secondarylensformationwaspresentin16outof17casesofthepituitaryimplantationexperimentsinwhichthepituitarytissueswereexposedtotheanteriorchamberfluid.Inonlyonecaseoutof23,didanotherimplantedtissue(liver)stimulatedsecondarylensformation.Theextentofsecondarylensformationwascorrelatedwiththeposition(closeness)oftheimplantinrelationshiptothedorsaliris.Inallcasesofsecondarylensformationfromthedorsalirisstimulatedbytissueimplants,thepolarityofthedevelopinglenswasreversedsothatthepoleofthefiberaxiswasdirectedtowardtheimplantratherthantheretina.Itappearsthattheectopicpituitaryproducesadiffusiblesubstancecapableofinitiatinglensformationfromthedorsalmarginoftheirisandcapableofdeterminingtheorientationofthefiberaxispoleofthedevelopinglens.
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[效力级别]  [学科分类] 生物科学(综合)
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