Studies on the mechanisms of histidase development in rat skin and liver: II. Alterations in enzyme levels and synthetic rates during development☆
[摘要] Thedivergentpostnataldevelopmentalcoursesofhistidasecatalyticactivityinratliverandskinofthesameanimals,viz.,aprogressiveriseinhepaticenzymeactivityandasimultaneousdeclineinepidermalactivity,hasbeenshowntobeaccompaniedbycorrespondingalterationsinthequantitiesofthesameenzymeprotein.Thesetissuespecificdevelopmentalchangesinenzymeamounthavebeenshown,furthermore,tobearesultofselectiveparallelalterationsinhistidasesyntheticrates.Ratesof[3H]leucineincorporationintohistidase,isolatedbyimmunoprecipitation,relativetoincorporationratesintototalsolubletissueprotein,increaseinliver,whilesimultaneouslydecreasinginskinofthesameanimalsduringpostnataldevelopment.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
