The projection patterns of the ventral horn to the hind limb during development☆
[摘要] HorseradishperoxidaseisinjectedintospecifiedregionsofthehindlimbbudofXenopuslaevistadpolesatserialstagesofdevelopment.Ventralhorncellsprojectingtotheinjectionsitesbecomelabelledbytheretrogradeaxonaltransportoftheenzyme.Bymappingthelabelledcellsthedevelopingpatternofprojectionoftheventralhorntothehindlimbischarted.Theearliestpatternsofprojectionsuggestthatthefirstmotoraxonstoinvadethelimbgrowtothemesenchymenearesttotheirpointofentry.Thereafter,however,theprojectionpatternsbegintoresembletheadultpatternsandindicatethatsubsequentlyinvadingaxonsareguidedtolimbregionsrelatedtothelocationoftheircellbodiesintheventralhorn.Furtherabruptchangesoftheprojectionpatternsleadingtothefinaladultpatternsareseenatthetimeofonsetofventralhorncelldegenerationandjustpriortotheonsetoflimbmovements.
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[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]