Clonal analysis of a genetically caused duplication of the anterior wing in Drosophila melanogaster
[摘要] Tworecessivelethalmutations,l(2)costandl(2)cos2,inDrosophilamelanogasteraredescribedwhichinthedoubleheterozygoteleadtotheformationoflargeduplicationsandoccasionaltriplicationsandquadruplicationsoftheanteriorpartofthewingbladeintheregionofthecostaandtriplerowofbristles.Clonalanalysiswithmarkermutantsfollowinginducedmitoticrecombinationshowedthatdisruptionofclonalgrowthwasconfinedtotheareaoftheduplication.Comparisonsweremadebetweenclonesizeintheduplication,clonesizeintheremainderofthewing,andthesizeoftheduplication.Therateofcelldivisionintheduplicationwassimilartothatinthemainwingbutcontinuedforalongerperiod.Variationinsizeoftheduplicationwasdependentupontheinitialnumberofcellsintheduplication.Cloneshapeintheduplicationresembledthatinthenormalwings.Theseresultsarediscussedintermsofthepossibilitythatlocalisedcelldeathinitiatestheduplication.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
