A study of ocular morphogenesis in the rat using [3H]thymidine autoradiography: Evidence for thymidine recycling in the developing retina
[摘要] Withtheuseoflightmicroscopicautoradiography,theincorporationandsubsequentdistributionof[3H]thymidinewithintheretinasofsequentiallystagedratembryoswasstudiedduringtheperiodwhenlargenumbersofcellsbecomenecroticandwereresorbedwithintheopticrudiment.Inthe48hrfollowinginjectionofisotopeonembryonicDay11,thenumberofgrainsoverlyingthedorsal,nondegenerateportionoftheretinadecreasedtoalowlevel,whereasventrally,wheretheretinabecomesintenselynecrotic,thegraincountsremainedatmuchgreaterlevels.Theresultsindicatethatthymidinemayberecycledwithinnormallydegenerateregionsoftheembryonicretina.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
