Regeneration of segment boundaries in Oncopeltus: Cell lineage
[摘要] ThesegmentboundaryofOncopeltusisastraightinterfacebetweenthecellsoftwosegmentalcompartments;itcoincideswithanabruptchangeofpigmentationandagrooveinthesurfaceofthecuticle.Whenasegmentboundaryisburntitisregeneratedbythecellsmigratingintothewound.Wedescribethecelllineageofthisprocess:thetwomassesofmigratingcellsfirstcontacteachotheronaconvolutedfrontier,butthissoonstraightens.Thenewboundaryformsexactlyattheinterfacebetweenthetwocellpopulations,withoutasinglecellstrayingacrosstheline.Evenwhenthecauteryisasymmetricand,asaconsequence,thecellsfromthedifferentsegmentsmeetatanabnormalposition,thesegmentboundaryisregeneratedatthisinterface.Afterextirpationortransplantationectopicboundariescanbeformedwithinasegment.Thesenewboundariesalsoactaslineagerestrictionsandstopminglingofcellsacrossthem.Ourresultssupportthehypothesisthattheintegrityandstraightnessofthecompartmentboundarydependoncellaffinities;thecellsinonepolycloneadheringmoretoeachotherthantothecellsoftheneighbouringpolyclone.Theremaybeagradientofcellaffinityineachsegment,withanabruptchangeatthesegmentboundary.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
