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Achromosomal cleavage of fertilized starfish eggs in the presence of aphidicolin☆
[摘要] Developmentoffertilizedeggsofstarfish,Asterinapectinifera,wasstudiedinthepresenceofaphidicolin,aspecificinhibitorofeukaryoticDNAsynthesis.Fertilizedeggscontinuedtocleaveeightorninetimesinthepresenceofaphidicolin,althoughthedelayofdevelopmentwasobservedandthesizeofblastomereswasnotequal.Thenucleusandchromosomeswereundetectableinblastomeresofembryosdevelopedinthepresenceofaphidicolin,althoughtheamphiasterwasclearlyvisibleinthecytoplasm.DNAsynthesisofsuchembryoswasnearlycompletelysuppressed.Thesemorphologicalandbiochemicallinesofevidenceindicatethattheabovecleavageisindependentofchromosomalreplication.Thestagewhenachromosomaldivisionsceaseandembryosbegintodiecorrespondstotheonsetofblastulation,suggestingthatinformationderivedfromtheembryogenomeisrequiredforblastulaformationinthisspecies.
[发布日期]  [发布机构] 
[效力级别]  [学科分类] 生物科学(综合)
[关键词]  [时效性] 
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