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The distal boundary of myogenic primordia in chimeric avian limb buds and its relation to an accessible population of cartilage progenitor cells
[摘要] Usingchimerasconsistingofchickembryosthathadreceivedsubstitutiongraftsofquailsomites,wehavedeterminedthedistalmostextensionofthemyogenicprimordiaintheoutgrowingwingbudat5daysofincubation.AtHamburger-Hamiltonstage25themostdistalpremusclecellisconsistently300μmormorefromtheapexofthewingmesoblast.Thestage25wingtipresemblesveryearlywholelimbbudsinnothavingproceededbeyondthemesenchymalstateorhavingexpressedmarkersofterminaldifferentiation.However,unlikeearlywholelimbbudsitisfreeofamyogenicsubpopulation.Wethereforeproposethatthestage25wingtipistheappropriatesystemforinvitroandmolecularstudiesofcartilagedifferentiation.
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[效力级别]  [学科分类] 生物科学(综合)
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