The correlation between the synthesis of skeletal muscle actin, myosin heavy chain, and myosin light chain and the accumulation of corresponding mRNA sequences during myogenesis☆
[摘要] ClonedcDNAprobeswereusedtomeasuretheaccumulationofmyosinheavychain,myosinlightchain2,andactinmRNAduringdifferentiationofratskeletalmusclecellcultures.Thiswascomparedwiththechangesintherateofsynthesisofthecorrespondingproteins.AccumulationofthosemRNAsequenceswasdetectableafewhoursbeforetheonsetofthephaseofcellfusion;however,themainincreaseinhybridizableRNAoccurredduringthephaseofrapidcellfusion.AclosecorrelationwasfoundbetweentheamountsofmRNAscodingfortheseproteinsandtherateofsynthesisoftheproteins.TheresultssuggestthattheactivationofstoredmRNAisnotamajormechanismforcontrollingthetimeatwhichtheseproteinsaresynthesized.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
