The effect of thyroxine on transparency and PAPS synthesis in the avian cornea☆
[摘要] Thenormalonsetofdevelopingcornealtransparency,whichbeginsonDay14ofchickembryogenesis,canbeacceleratedbytheinvivoapplicationofexogenousthyroxine,asoriginallydemonstratedbyCoulombreandCoulombre(1964,Exp.EyeRes.3,105–114).Whenthyroxine(5μg)isinjectedatDay6,measurementsof35SO2−4incorporationbycornealhomogenatesindicatethatsynthesisof3′-adenosinephosphosulfate(APS)inthecorneaisincreasedatDay8,butnotthatof3′-phosphoadenosine-5′-phosphosulfate(PAPS).InjectionofhormoneatDay9resultsinaprecociousincreaseincornealtransparencyatDay12andacorrespondingincreaseinthesynthesisofAPSandPAPS.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
