Positional control of nuclear differentiation in paramecium
[摘要] Nuclearreorganization,whichresultsinthedifferentiationbetweenmacronuclearanlagenandmicronucleiduringautogamyorconjugationinParameciumtetraurelia,wascomparedinwild-typecellsandintwomutants,mic44andkin241,whichformabnormalnumbersofmacronuclearanlagenandmicronuclei.Ourobservationsshowthatallmacronuclearanlagenderivefromthenucleipositionedattheposteriorpoleofthecellatthesecondpostzygoticdivision.Thisposteriorlocalizationistransientandcorrelatedwithamarkedchangeincellshapeanddecreaseofcelllength.Theseresultssuggestthatcytoplasmicorcorticalfactorspreciselylocatedintheposteriorpoleareessentialtotriggermacronucleardifferentiationandthatthecontrolofnuclearpositioningisdependentuponprecisemodificationsofcellshape.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
