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Reconstruction of brain tissue from cell suspensions: II. Specific enhancement of aggregation of embryonic cerebral cells by supernatant from homologous cell cultures☆
[摘要] Acell-freesupernatantfromshort-termmonolayerculturesof14-dayembryonicmousecerebrumcellsmarkedlyandspecificallyenhancedthehistotypicaggregationofsuspensionsofdissociatedcerebrumcellsfrommouseandfromchickembryos.Itdidnothavethiseffectoncellsfromotherbrainregions,orfromnonnervoustissuesfromeitherspecies;itseffectwassomewhatgreaterontheaggregationofmousecerebrumcellsthanofchickcerebrumcells.Itsactionwasconcentration-dependentandcriticallydependentontheembryonicageofthedonorcellsandtheaggregatingcells.Theresultsarediscussedintermsofcellsurfaceinteractionsandtheirimplicationsforneuralhistogenesisanddifferentiation.
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[效力级别]  [学科分类] 生物科学(综合)
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