Reconstruction of brain tissue from cell suspensions: II. Specific enhancement of aggregation of embryonic cerebral cells by supernatant from homologous cell cultures☆
[摘要] Acell-freesupernatantfromshort-termmonolayerculturesof14-dayembryonicmousecerebrumcellsmarkedlyandspecificallyenhancedthehistotypicaggregationofsuspensionsofdissociatedcerebrumcellsfrommouseandfromchickembryos.Itdidnothavethiseffectoncellsfromotherbrainregions,orfromnonnervoustissuesfromeitherspecies;itseffectwassomewhatgreaterontheaggregationofmousecerebrumcellsthanofchickcerebrumcells.Itsactionwasconcentration-dependentandcriticallydependentontheembryonicageofthedonorcellsandtheaggregatingcells.Theresultsarediscussedintermsofcellsurfaceinteractionsandtheirimplicationsforneuralhistogenesisanddifferentiation.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]