Stimulation of adenyl cyclase in pupal wing epidermis by β-ecdysone☆
[摘要] Theinjectionofβ-ecdysoneintochilledHyalophoragloveripupaeresultedinthestimulationofadenylcyclaseactivityinthewingepidermisasmeasuredbytheincorporationoflabelintocyclicAMPfromaprelabeledendogenouspool.Stimulationwasalsoobtainedinpupalwingsinvitroandinwingepidermalhomogenates.Althoughthesequenceofresponsestoβ-ecdysoneinvitrodependedonthecompositionoftheincubationmedium,thestimulationofcyclicAMPsynthesisalwaysprecededincreasesintheratesofRNAandproteinsynthesis.Theincreaseinadenylcyclaseactivityistheearliestmetaboliceventthusfardiscernedasaresultofβ-ecdysoneaction.Itissuggestedthatβ-ecdysonestimulatesadenylcyclase(andguanylcyclase)butthatthehormonealsoexertseffectsontargetcellsindependentofthecyclicAMPsystem.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
