Fine structure of mutant (muscular dysgenesis) embryonic mouse muscle☆
[摘要] Thisinvestigationisconcernedwiththeultrastructureofembryonicmusclecellsinmicehomozygousforthemutationmdg(musculardysgenesis).Theearliestabnormalitiesaredetectedatagestationalageof14dayswhenthesarcoplasmicreticulumofmutantcellsbeginstoappeardilated.Inlaterstagesswollensarcoplasmicreticulumisseeninallmusclecellsaswellasnuclearabnormalitiesandcelldeath.Thecorrelationbetweentheultrastructuralabnormalitiesofthesarcoplasmicreticulumandtheothercellularabnormalitiesisdiscussed,aswellasthepossiblerelevanceofthestructuralabnormalitiestothetotalabsenceofmusclefunctioninmutanthomozygotes.
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[效力级别] [学科分类] 生物科学(综合)
[关键词] [时效性]