Myocardial cell shape change as a mechanism of embryonic heart looping☆
[摘要] Measurementsoflocalareachangesoftheembryonicmyocardialsurfaceindicatethattheprospectiverightsideexpandsduringlooping.Observationsfromsectionedspecimensshowingthattherightsideofthemyocardiumalsobecomesthinnerduringloopingsuggestthattheincreaseinareamayresultfrommyocardialcellflattening.Lightmicroscopicexaminationofsilverimpregnatedheartssuggeststhatindividualcellsincreaseinapicalsurfaceareaastherightsidebecomesconvex.Computer-assistedanalysesofscanningelectronmicrographsshowthatcellsoftheprospectiveconvexsideincreasesignificantlyinapicalsurfaceareaduringlooping,althoughtherelativealignmentoftheirmajorsurfaceaxesremainsunchangedandrandom.Myocardialcellsoftheconcavesideofthehearthaveasmallerapicalsurfaceareaandtheirmajorsurfaceaxesarealignedcircumferentiallyinrelationtotheheart.Weproposethattheseregionalchangesincellshapeandalignmentmediateheartlooping.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
