Experimental studies on the development of the bursa of Fabricius
[摘要] AnanalysisoftheoriginoflymphoidcellsinthedevelopingbursaofFabriciushasbeenmadeusingachromosomemarkertechniqueincombinationwithvariousexperimentalproceduresincludingparabiosisofembryosofsimilarmajorhistocompatibilitytype,twinembryostudies,transplantationofbursalrudimentstothechorioallantois,andhormonalmodificationofbursaldevelopment.Theresultsindicatethatthemajorityofbursallymphocytesarederivedfromblood-borneprogenitorcellswhichenterthebursalprimordiumduringembryogenesis.Testosteronetreatmentdoesnotlimitthesupplyofthesecellsbutprobablyalterstheenvironmentinwhichtheyproliferateandmature.Thestructureandsiteoforiginoftheprogenitorcellsisunknown,andtheseremainpointsforfutureinvestigation.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
