In vitro studies on chondrogenesis: the uptake of radioactive sulfate during cartilage induction☆
[摘要] 1.1.Theinductionofchickvertebralcartilagebyspinalcordandnotochordwasstudiedintissueculturewiththeuseofradioactivesulfate.Theincorporationofradioactivesulfateintotheinducedcartilagewasusedtodetecttheformationofsulfatedpolysaccharides.2.2.Chondroitinsulfate(s)wereextractablefromtheculturesonlywhenadistinguishablecartilagematrixwaspresent.Itwasconfirmedthatintheabsenceofaninducingagent(spinalcordornotochord),somitesformedneithercartilagenoranycharacteristicmacromolecularconstituentsofcartilage(collagenandchondroitinsulfates).3.3.Chondroitinsulfate(s)weretheonlyacidpolysaccharidespresentintheinducedcartilage.Keratosulfate,inadditiontochondroitinsulfate,isdetectedinolderchickvertebralcartilage.Thepresenceofchondroitinsulfatewasdetectedindependentlybyanalysisforuronicacid.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物科学（综合）
[关键词] [时效性]
