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Influence of an eccentric epidermal cap on limb regeneration in Amblystoma larvae☆
[摘要] 1.1.TheepidermalcapoftheregeneratingforelimboflarvalAmblystomawasinducedtobecomeeccentricallylocatedattheposteriorborderoftheamputationsurfacebymeansofaskinexcision(12mmlongby13mmwide)attheposterioredgeoftheamputationsurface.Healingoftheskinexcisionwoundbyepidermalmigration,particularlyfromtheepidermiscoveringtheamputationsurface,carriedtheepidermalcaptothepostaxialborderofthelimbtip.2.2.Blastermalcellsaggregatedbeneaththeeccentricepidermalcaptoformacorrespondinglyeccentricblastemawhichdevelopedintoanasymmetricalregenerate.3.3.Eccentricepidermalcapswereinducedinregressedlimbsafteralllimbtissueshadcompletelydedifferentiated.Blastemalcellsaggregatedbeneaththeeccentricepidermalcapstoproduceeccentricblastemataandregenerates.Thustheeccentricepidermalcapinducedacorrespondingeccentricityofregenerativeoutgrowthnotbyadifferentialhistolysisoflimbtissues,butbycontrollingtheaggregationofblastemalcells.
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[效力级别]  [学科分类] 生物科学(综合)
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